5-Amino-1MQ
Small-molecule NNMT inhibitor studied for its potential role in metabolism, fat cell regulation, and cellular energy.
Research Areas
Scientific Background
5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme overexpressed in adipose tissue during metabolic dysfunction. By inhibiting NNMT, research suggests it may increase cellular NAD+ and SAM levels, influencing adipocyte energy metabolism.
Purity & Provenance
Why quality matters for research validity
5-Amino-1MQ is a small-molecule quinolinium compound. Verify ≥98% purity via HPLC.
Areas of Investigation
Laboratory Information
Technical specifications for research settings
This compound is intended for qualified scientific research only. Not for human or veterinary use. Not for diagnostic or therapeutic applications. Researchers must comply with all applicable regulations in their jurisdiction.
Store at -20°C. Protect from light and moisture.
Lyophilized powder
>98% by HPLC
Soluble in DMSO and water
For in vitro metabolic research applications.
Deepen Your Research
Published literature and clinical trial registries
Published Literature
Neelakantan et al. (2018, Biochemical Pharmacology) characterized 5-Amino-1MQ as a selective NNMT inhibitor. Kraus et al. (2014, Nature) established NNMT's role in adipose tissue metabolism, providing the rationale for NNMT inhibition research.
Regulatory Classification
5-Amino-1MQ is a research compound not approved by the FDA. Available for qualified research purposes only.
Important Research Notice
This information is compiled from scientific literature for educational purposes only. This website does not sell, distribute, or recommend any compounds for human use. All compounds discussed are for qualified research purposes only.