Follistatin 344
Glycoprotein studied for its role in binding and inhibiting myostatin, a key regulator of muscle growth.
Research Areas
Scientific Background
Follistatin 344 is an isoform of follistatin, a glycoprotein that binds and neutralizes members of the TGF-β superfamily, most notably myostatin (GDF-8), a negative regulator of skeletal muscle mass. By inhibiting myostatin, follistatin is studied as a potential driver of muscle hypertrophy and regeneration.
Purity & Provenance
Why quality matters for research validity
Follistatin 344 is a glycoprotein isoform. Research-grade material should be verified ≥95% purity via HPLC/SDS-PAGE.
Areas of Investigation
Laboratory Information
Technical specifications for research settings
This compound is intended for qualified scientific research only. Not for human or veterinary use. Not for diagnostic or therapeutic applications. Researchers must comply with all applicable regulations in their jurisdiction.
Store lyophilized at -20°C. Protect from light.
Lyophilized powder
>95% by HPLC
Soluble in bacteriostatic water
For in vitro muscle research applications.
Deepen Your Research
Published literature and clinical trial registries
Published Literature
Lee & McPherron (2001, PNAS) established myostatin as a negative muscle regulator and follistatin's role in its inhibition. Gilson et al. and others examined follistatin-driven muscle growth in preclinical models, showing significant increases in muscle mass.
Regulatory Classification
Follistatin 344 is a research compound not approved by the FDA. Available for qualified research purposes only.
Important Research Notice
This information is compiled from scientific literature for educational purposes only. This website does not sell, distribute, or recommend any compounds for human use. All compounds discussed are for qualified research purposes only.