KPV
Alpha-MSH-derived tripeptide studied for its anti-inflammatory properties, particularly in gut and skin research.
Research Areas
Scientific Background
KPV (Lys-Pro-Val) is the C-terminal tripeptide fragment of alpha-MSH. It exhibits anti-inflammatory activity independent of melanocortin receptors, appearing to act intracellularly to inhibit pro-inflammatory NF-κB signaling. It has been studied particularly in the context of intestinal and dermal inflammation.
Purity & Provenance
Why quality matters for research validity
KPV is a tripeptide (Lys-Pro-Val). Verify HPLC ≥98% purity and sequence confirmation.
Areas of Investigation
Laboratory Information
Technical specifications for research settings
This compound is intended for qualified scientific research only. Not for human or veterinary use. Not for diagnostic or therapeutic applications. Researchers must comply with all applicable regulations in their jurisdiction.
Store lyophilized at -20°C. Protect from light.
Lyophilized powder
>98% by HPLC
Soluble in water and saline
For in vitro anti-inflammatory research applications.
Deepen Your Research
Published literature and clinical trial registries
Published Literature
Dalmasso et al. (2008, Gastroenterology) demonstrated that KPV reduces intestinal inflammation via PepT1-mediated uptake in colonic cells. Additional research examined its role in downregulating pro-inflammatory cytokines in models of colitis.
Regulatory Classification
KPV is a research compound not approved by the FDA. Available for qualified research purposes only.
Important Research Notice
This information is compiled from scientific literature for educational purposes only. This website does not sell, distribute, or recommend any compounds for human use. All compounds discussed are for qualified research purposes only.